{"id":53743,"date":"2025-12-27T03:45:42","date_gmt":"2025-12-27T03:45:42","guid":{"rendered":"https:\/\/gyalchisarshog.com\/?p=53743"},"modified":"2025-12-27T03:45:46","modified_gmt":"2025-12-27T03:45:46","slug":"indias-first-gene-edited-sheep-just-turned-one-hows-it-doing","status":"publish","type":"post","link":"https:\/\/gyalchisarshog.com\/?p=53743","title":{"rendered":"India&#8217;s first gene-edited sheep just turned one. How&#8217;s it doing?"},"content":{"rendered":"\n<p>BBC:   <\/p>\n\n\n\n<p>India&#8217;s first gene-edited sheep recently turned a year old and researchers who developed it say it&#8217;s doing well.<\/p>\n\n\n\n<p>Born on 16 December last year in Indian-administered Kashmir, the sheep has been named Tarmeem \u2013 the Arabic word for modification or editing.<\/p>\n\n\n\n<p>Tarmeem is housed in a private enclosure at the Sher-e-Kashmir Agricultural University in the region&#8217;s main city Srinagar along with its non-edited twin sister.<\/p>\n\n\n\n<p>Researchers at the university told the BBC that they used CRISPR technology &#8211; a biological system for altering DNA \u2013 to develop it.<\/p>\n\n\n\n<p>Basically what it allows scientists to do is use it like a pair of scissors to chop off bits of a gene that cause weaknesses or diseases.<\/p>\n\n\n\n<p>&#8220;We extracted a number of embryos from pregnant sheep and edited a specific gene &#8211; known as the myostatin gene &#8211; which negatively affects muscle growth,&#8221; researcher Dr Suhail Magray told the BBC.<\/p>\n\n\n\n<p>The embryos or fertilised eggs were kept in controlled laboratory conditions for two-three days after which they were transferred to a female sheep &#8211; or the foster recipient.<\/p>\n\n\n\n<p>&#8220;And then nature took over &#8211; 150 days later, lambs were born,&#8221; he said. &#8220;Our aim was to increase the muscle mass in sheep and by knocking out the myostatin gene, we successfully managed to do that,&#8221; he added.<\/p>\n\n\n\n<p>After Tarmeem turned one earlier this month, Prof Riaz Shah, the dean of faculty of veterinary sciences and principal investigator on the project, gave the BBC a status update.<\/p>\n\n\n\n<p>&#8220;It&#8217;s growing well, showing normal physiological, biochemical and physical parameters,&#8221; he said. &#8220;Tarmeem&#8217;s muscle growth has expectedly shown significant increase &#8211; about 10% &#8211; in comparison to its non-edited twin. I think it is likely to increase further with age.&#8221;<\/p>\n\n\n\n<p>Experimentation is going on to evaluate its health and survival and the sheep is kept in a secure environment under strict surveillance, Prof Shah said, adding that they have submitted a research project to the government for funding support.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>BBC: India&#8217;s first gene-edited sheep recently turned a year old and researchers who developed it say it&#8217;s doing well. Born on 16 December last year in Indian-administered Kashmir, the sheep has been named Tarmeem \u2013 the Arabic word for modification or editing. Tarmeem is housed in a private enclosure at the Sher-e-Kashmir Agricultural University in the region&#8217;s main city Srinagar along with its non-edited twin sister. Researchers at the university told the BBC that they used CRISPR technology &#8211; a biological system for altering DNA \u2013 to develop it. Basically what it allows scientists to do is use it like&#8230; <\/p>\n","protected":false},"author":1,"featured_media":53744,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-53743","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-in-english"],"_links":{"self":[{"href":"https:\/\/gyalchisarshog.com\/index.php?rest_route=\/wp\/v2\/posts\/53743","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gyalchisarshog.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gyalchisarshog.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gyalchisarshog.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gyalchisarshog.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=53743"}],"version-history":[{"count":1,"href":"https:\/\/gyalchisarshog.com\/index.php?rest_route=\/wp\/v2\/posts\/53743\/revisions"}],"predecessor-version":[{"id":53745,"href":"https:\/\/gyalchisarshog.com\/index.php?rest_route=\/wp\/v2\/posts\/53743\/revisions\/53745"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gyalchisarshog.com\/index.php?rest_route=\/wp\/v2\/media\/53744"}],"wp:attachment":[{"href":"https:\/\/gyalchisarshog.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=53743"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gyalchisarshog.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=53743"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gyalchisarshog.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=53743"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}